Liver disease death risk doubled in low-income countries: Lancet study, ET HealthWorld

Liver disease death risk doubled in low-income countries: Lancet study, ET HealthWorld

New Delhi: danger of death for hospitalized for liver disease Patients with hypotension or hypotension more than twice as likely lower middle income countries compared to high income countriesAccording to a study that analyzed data from 25 countries, including India. This study was published in The journal. Lancet Gastroenterology & hepatology journalwas found to be at high risk of low income countries This is primarily due to limited access to diagnostics and diagnostics. therapeutic resources.

Liver disease often occurs when the liver experiences chronic inflammation due to obesity, excessive alcohol consumption, viral hepatitis, or a combination thereof.

Over time, this inflammation can lead to severe scarring of the liver, known as cirrhosis, which can disrupt liver function and ultimately lead to liver failure.

Liver disease is one of the world’s leading causes of death, currently killing two million people each year, and is expected to claim many more in the future, researchers say.

“A functioning liver is very important for our health because the liver is linked to many aspects of body function,” said professor Jasmohan Bajaj from the university. Virginia Commonwealth University US School of Medicine.

“Anything that affects the liver can affect the operation of other organs and systems in the body, such as the immune system, cardiovascular system, brain, gut and kidneys,” Bajaj said.

Professors Bajaji Chowdhury and Ashok K. Chowdhury and colleagues at the Institute of Liver and Biliary Sciences, New Delhi, investigated the method. danger of death The impact of cirrhosis varies from country to country, and the underlying factors behind such inequalities also differ.

“Most cirrhosis studies focus on the north or specific regions of the world and do not consider differences in public health resources. It’s one of the only prospective studies to analyze,” he said. Bajaj is the lead author of the study.

The research team collected and analyzed medical data from nearly 4,000 people with cirrhosis at 90 medical centers in 25 countries on six continents.

Data show that patients with cirrhosis in low-income countries were more than twice as likely to die during hospitalization or within 30 days after discharge compared with patients treated in high-income countries.

“These results are very shocking and sobering. We did not expect such a large difference in cirrhosis mortality, but this is a significant step forward in tackling advanced liver disease globally. shows that we are not on a level playing field,” Bajaj said.

The study also highlights that global differences in health care resources may contribute to differences in mortality rates.

For example, survey data show that patients with cirrhosis in low-income countries cannot and may not have access to relevant diagnoses, medications, treatments, ICU care, and liver transplantation while hospitalized. shown to be low.

Patients with cirrhosis in low-income countries are also more likely to be hospitalized in the later stages of their disease and more likely to suffer from gastrointestinal bleeding, hepatitis B flare-ups, or infections, all of which cannot be provided with adequate care. It is a preventable condition, the researchers said. .

The findings may reflect a lack of outpatient care and personal financial resources for patients, the researchers said.

“The important thing to understand is that cirrhosis patient care should begin before the need to go to the hospital is over. There are three key factors to prevent ,” added Bajaj.

  • Published May 25, 2023 at 3:21 PM (IST)

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